One By Kose Japan SERUM SHIELD (40g/1.3oz.) wrinkle care cream

ONE BY KOSÉ Medicated Moisturizing Wrinkle‑Care Cream is formulated with Japan’s first active ingredient “Rice Power® No.11+(Plus)”—recognized by Japan’s Ministry of Health, Labour and Welfare for improving both skin moisture and fine lines. It is a non‑sticky, medicated high‑moisture‑sealing cream, powerfully targeting those troubled by both skin dryness and fine wrinkles.
Improves skin’s moisture‑retention ability
The main component of intercellular lipids, “Ceramide,” decreases with age, weakening the skin’s ability to retain moisture. Even if you replenish moisture, it easily evaporates. Rice Power® No.11+(plus) enhances ceramide‑producing capacity, effectively improving skin’s moisture‑retention function—locking in hydration and boosting skin’s own moisturizing power.
Targets epidermis, basement membrane, and dermis to comprehensively improve fine lines
・Epidermis: Promotes production of NMF (Natural Moisturizing Factor), hyaluronic acid, and ceramides.
・Basement membrane & dermis: Increases basement‑membrane collagen and inhibits its breakdown.
Just 8 weeks of continuous use can lead to visible wrinkle improvement～